Coating formulation for medical coating
AssigneeDsm IP Assets B.V.
InventorsAylvin Jorge Angelo Athanasius DIAS, Edith Elisabeth M. VAN DEN BOSCH, Peter BRUIN, Marnix ROOIJMANS, Rudolfus Antonius Theordus Maria VAN BENTHEM
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Abstract
The invention relates to a coating formulation for preparing medical coating, which coating formulation comprises (a) at least one multifunctional polymerizable compound according to a formula (I), wherein G is a residue of a polyfunctional compound having at least n functional groups, wherein each R1 and each R2 independently represents hydrogen or a group selected from substituted and unsubstituted hydrocarbons which optionally contain one or more heteroatoms, and wherein n is an integer having a value of at least 2; and (b) at least one inhibitor.
Claims20
A method of forming on a medical device or component a hydrophilic medical coating, the method comprising:
- (I) applying to at least one surface of the medical device or component a coating formulation which comprises:
- (a) at least one multifunctional polymerizable compound according to formula (1):
- wherein G is a polymer comprising at least one polyethylene glycol block and is a residue of a hydrophilic polyfunctional compound having at least n functional groups;
- wherein each R1 and each R2 independently represents hydrogen, wherein n is an integer having a value of 2-8, and wherein the multifunctional polymerizable compound according to formula (1) has a number average molecular weight (Mn) of from 500 to 10,000 g/mol;
- and
- (b) at least one free-radical photo-initiator;
- (II) allowing the coating formulation to cure by exposing, the formulation to electromagnetic radiation thereby activating the free-radical photo-initiator;
- and
- (III) obtaining a hydrophilic medical coating on the at least one surface of the medical device or component, the hydrophilic medical coating having a thickness of from 0.1-200 μm.
The method according to claim I, the coating formulation further comprising a functional. polymer (c).
Dependencies are inferred from the claim text.