Sweet taste receptor antagonist compositions
AssigneeFour LLC
InventorsRobert L. GOLDSTEIN, Grant DUBOIS, Arianne PERRY
Life of this patent
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Abstract
The present disclosure relates to compositions comprising gymnemic acid, together with a form of zinc to block the unpleasant bitter taste of gymnemic acid as well as to extend the sweet taste blocking properties of gymnemic acid, resulting in palatable compositions for delivery to the oral cavity to block sweet taste receptors located therein. The present disclosure also relates to methods of reducing sugar consumption and reducing calorie intake via administration of such compositions to a subject.
Claims31
1-25. (canceled)
A composition comprising at least one form of gymnemic acid and at least one form of zinc, wherein a weight ratio of the at least one form of gymnemic acid to zinc ion in the at least one form of zinc is less than 5.1.
A lingual delivery form comprising at least one form of gymnemic acid and at least one form of zinc, wherein the at least one form of gymnemic acid is present in the range of from about 0.1 mg to about 10 mg and the at least one form of zinc is present in the range of about 1 mg to about 10 mg.
A method of reducing calorie intake, comprising administering a composition comprising at least one form of gymnemic acid and at least one form of zinc, wherein a weight ratio of the at least one form of gymnemic acid to zinc ion in the at least one form of zinc is less than 5.1.
A method of reducing dental caries, comprising administering a composition comprising at least one form of gymnemic acid and at least one form of zinc, wherein a weight ratio of the at least one form of gymnemic acid to zinc ion in the at least one form of zinc is less than 5.1.
Dependencies are inferred from the claim text.