Use of angiotensin ii (aii) receptor agonists to prevent or reduce hemodialysis-associated skeletal muscle cramps
AssigneeATKINSON, Arthur J.
InventorArthur J. ATKINSON, JR.
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Abstract
Disclosed herein is a therapeutic intervention to prevent, reduce, or treat hemodialysis-associated skeletal muscle cramps by administering All receptor agonists or other pharmacologic agents that augment homeostatic responses to hemodialysis while preventing derecruitment of skeletal muscle capillaries.
Claims8
A method of preventing, reducing, or treating cramping during hemodialysis, said method comprising administering to a subject an effective amount of a pharmacologic agent that enhances blood vessel constriction on the venous side of capillaries to a greater extent than on the arterial side of capillaries.
A method of preventing, reducing, or treating cramping during hemodialysis, said method comprising administering to a subject an effective amount of a pharmacologic agent that enhances the activity of the renin-angiotensin system in said subject.
Dependencies are inferred from the claim text.