# US 2016/0256705 A1 · Reduced profile and enhanced flexibility delivery catheters for light activated agents

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- Number: US 2016/0256705 A1
- Document ID: US20160256705A1
- Status: Published application
- Kind: A1
- Application number: 15/158,513
- Filed: 2016-05-18
- Published: 2016-09-08
- Earliest claimed: 2008-08-13
- Assignees: Abbott Cardiovascular Systems Inc.
- Applicants: Abbott Cardiovascular Systems Inc.
- Inventors: William E. WEBLER, JR.; Richard R. Newhauser
- Web page: https://patentgrep.com/patent/US20160256705A1

## CPC

- A61N 5/062: {Photodynamic therapy, i.e. excitation of an agent}
- A61B 1/00163: {Optical arrangements (A61B1/002, A61B1/06 take precedence)}
- A61B 1/00165: {with light-conductive means, e.g. fibre optics (A61B1/07 takes precedence)}
- A61B 18/18: by applying electromagnetic radiation, e.g. microwaves
- A61M 25/0084: {being one or more injection needles}
- A61M 25/0662: {Guide tubes}
- A61N 5/0601: {Apparatus for use inside the body}
- A61B 2018/1807: {using light other than laser radiation}
- A61M 2025/0089: {Single injection needle protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip}
- A61M 2025/0681: {Systems with catheter and outer tubing, e.g. sheath, sleeve or guide tube}
- A61N 2005/0602: {for treatment of blood vessels}
- A61N 2005/0612: {using probes penetrating tissue; interstitial probes}
- A61N 2005/063: {comprising light transmitting means, e.g. optical fibres}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A delivery catheter for delivery, then photo-activation of photo sensitive material has a photo-sensitive substance-delivery part and an activation part. The catheter delivers substances such as biomaterials to a target site, followed by illumination of the target using optics located at the distal tip of the catheter which are optically coupled to an extracorporeal light source. The light may be delivered by a single or multi-lumen needle, or a separate light guide passed over the catheter.

## Claims

### Claim 1

A method for treating tissue, the method comprising:
placing a catheter distal end adjacent the tissue, the catheter including a needle tip and a light-emitting portion;
embedding the needle tip into the tissue;
dispensing a photo-sensitive substance into the tissue;
displacing the light emitting portion to enable light from the light emitting portion to reach the tissue, and
photo-activating the substance in the tissue using the light from the light emitting portion.

### Claim 2 (depends on 1)

The method of claim 1, wherein displacing the light emitting portion includes displacing a fiber optic within a bore of the needle.

### Claim 3 (depends on 1)

The method of claim 1, wherein displacing the light emitting portion includes displacing a sheath having a fiber optic over the catheter.

### Claim 4 (depends on 1)

The method of claim 1, wherein the displacing the light emitting portion and the placing of the catheter distal end are performed by moving a spiral fiber optic towards the tissue.

### Claim 5

A method for treating tissue, the method comprising:
disposing a catheter tip adjacent the tissue;
injecting a photo-sensitive substance into the tissue from a tip of a needle; and
transmitting light energy to the tissue using the tip of the needle.

### Claim 6 (depends on 5)

The method of claim 5, wherein the transmitting includes transmitting the light energy through a solid medium.

### Claim 7 (depends on 5)

The method of claim 5, wherein the transmitting includes transmitting the light energy through a fluid medium.

### Claim 8 (depends on 5)

The method of claim 5, further comprising curing the substance injected into the tissue by the transmitted light energy.

### Claim 9 (depends on 5)

The method of claim 5, wherein the needle has a lumen extending through the needle, and the transmitting light energy and injecting the photo-sensitive substance both occur within the lumen.

### Claim 10 (depends on 9)

The method of claim 9, wherein the transmitting includes transmitting the light energy through a fiber optic.

### Claim 11 (depends on 9)

The method of claim 9, wherein the transmitting includes transmitting the light energy through a fluid.