# US 2016/0256641 A1 · Delivery System for Metered Dose Inhalers > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2016/0256641 A1 - Document ID: US20160256641A1 - Status: Published application - Kind: A1 - Application number: 15/057,907 - Filed: 2016-03-01 - Published: 2016-09-08 - Earliest claimed: 2015-03-02 - Inventors: Edward Lisberg - Web page: https://patentgrep.com/patent/US20160256641A1 ## CPC - A61M 15/0088: {with variable volume} - A61M 15/0021: {Mouthpieces therefor} - A61M 15/009: {using medicine packages with incorporated spraying means, e.g. aerosol cans (pocket atomiser of the injector type A61M11/08)} - A61M 11/003: {by passing the aerosol trough sieves or filters} - A61M 2205/183: the sound being generated pneumatically - A61M 2205/3334: Measuring or controlling the flow rate - A61M 2205/44: making noise when used incorrectly - A61M 2205/581: by audible feedback - A61M 2205/75: with filters - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract A device for delivering medications with hydroflouroalkane propellant driven metered-dose inhalers (MDIs). The device includes a collapsible bag to which is attached a bidirectional mouthpiece and an adaptor that receives the MDI. The mouthpiece contains a reed that functions as an audible signal and a screen to prevent inhalation of unwanted particles. When the MDI is triggered it discharges the medication into the collapsible bag which is then inhaled by the user through the mouthpiece. This collapses the bag. The reed emits an audible sound if the user inhales above a predetermined flow rate to maximize medication delivery and ensure dose-to-dose consistency. ## Claims ### Claim 1 A delivery device for metered dose inhalers for providing a drug to a user through inhalation, the device comprising: a collapsible airbag having an open top end and a bottom end, the bottom end sealed to prevent the passage of air into or out from the airbag from the bottom, a cap with two openings mounted on the open top, the cap having sealing means to provide an air tight seal between the cap and the open top of the flexible air bag, a tubular mouthpiece having a proximal end suitable for the user placing the proximal end in the user's mouth, and a distal end mounted in one of said openings, the tubular mouthpiece in fluid communication with the flexible bag, a filtering screen mounted in the tubular mouthpiece; an air actuated audible sounding mechanism mounted in the tubular mouthpiece for providing an audible signal when the flow rate of air passing through the mechanism exceeds a predetermined flow rate to signal the user to decrease the inhalation rate to maximize the utilization of the drug, an upstanding collar in the other of said openings in the cap, a metered dose inhaler adaptor mounted on the collar, the metered dose inhaler adaptor having a centrally disposed flexible member, an opening in the centrally disposed flexible member adapted for receiving various sized metered dose inhaler canisters in substantially fluid tight engagement, the metered dose inhaler dispensing an aerosol spray containing a predetermined amount of a drug through the adaptor into the flexible bag, whereby the user inhales the medication through the mouthpiece and the filtering screen filters unwanted particles and the audible sounding system provides an audible signal when user inhales the air with the drug from the flexible airbag through the mouthpiece exceeds the predetermined fluid flow rate. ### Claim 2 (depends on 1) The delivery device for metered dose inhalers of claim 1, wherein said audible sounding mechanism is a reed that vibrates producing an audible sound when the flow rate of the air from the flexible bag exceeds the predetermined fluid flow rate. ### Claim 3 (depends on 2) The delivery device for metered dose inhalers of claim 2 wherein said reed produces a whistling sound when the flow rate of the air from the flexible bag exceeds the predetermined fluid flow rate. ### Claim 4 (depends on 3) The delivery device for metered dose inhalers of claim 3 wherein the flexible bag is low density polyethylene. ### Claim 5 (depends on 1) The delivery device for metered dose inhalers of claim 1 wherein the mouthpiece has locking tabs in the distal end and the opening has slots to receive the locking tabs whereby the mouthpiece is removably attached to the opening for ease of installation for use and removal for cleaning. ### Claim 6 (depends on 1) The delivery device for metered dose inhalers of claim 1 wherein the collar has keyways and the metered dose inhaler adaptor has internal keys that are received in the keyways to align the metered dose inhaler adaptor with the end cap so that the opening in the centrally disposed flexible member is aligned to receive the metered dose inhaler canister. ### Claim 7 (depends on 1) The delivery device for metered dose inhalers of claim 1 wherein the collapsible airbag gives the user a visual indication that all of the drug has been inhaled when the collapsible airbag is substantially collapsed. ### Claim 8 (depends on 1) The delivery device for metered dose inhalers of claim 1 and further comprising a channel in the metered dose inhaler adaptor that receives the collar to securely attach the metered dose inhaler adaptor to the collar. ### Claim 9 A delivery device for metered dose inhalers for providing a drug to a user through inhalation, the device comprising: a collapsible airbag having an open top end and a bottom end, the bottom end sealed to prevent the passage of air into or out from the airbag from the bottom, a cap with two openings mounted on the open top, the cap having sealing means to provide an air tight seal between the cap and the open top of the flexible air bag, a tubular mouthpiece having a proximal end suitable for the user placing the proximal end in the user's mouth, and a distal end mounted in one of said openings, the tubular mouthpiece in fluid communication with the flexible bag, a filtering screen mounted in the tubular mouthpiece; a reed mounted in the tubular mouthpiece for providing an audible signal when the flow rate of air passing through the mechanism exceeds a predetermined flow rate to signal the user to decrease the inhalation rate to maximize the utilization of the drug, locking tabs in the distal end and complementary receiving slots in the opening to receive the locking tabs whereby the mouthpiece is removably attached to the opening for ease of installation for use and removal for cleaning, an upstanding collar in the other of said openings in the cap, the collar having a keyway in the collar, a metered dose inhaler adaptor mounted on the collar, the metered dose inhaler adaptor having a centrally disposed flexible member, an opening in the centrally disposed flexible member adapted for receiving various sized metered dose inhaler canisters in substantially fluid tight engagement, internal keys in the adaptor that are received in the keyways in the collar to align the metered dose inhaler adaptor with the end cap so that the opening in the centrally disposed flexible member is aligned to receive the metered dose inhaler canister, the metered dose inhaler dispensing an aerosol spray containing a predetermined amount of a drug through the adaptor into the flexible bag, whereby the user inhales the medication through the mouthpiece and the filtering screen filters unwanted particles and the reed provides an audible signal when user inhales the air with the drug from the flexible airbag through the mouthpiece exceeds the predetermined fluid flow rate.