# US 2016/0256508 A1 · Compositions containing nitro fatty acids > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 2016/0256508 A1 - Document ID: US20160256508A1 - Status: Published application - Kind: A1 - Application number: 15/157,674 - Filed: 2016-05-18 - Published: 2016-09-08 - Earliest claimed: 2008-12-31 - Assignees: Nitromega Corp. - Applicants: Nitromega Corp. - Inventors: Raymond A. Miller - Web page: https://patentgrep.com/patent/US20160256508A1 ## CPC - A61K 36/63: Oleaceae (Olive family), e.g. jasmine, lilac or ash tree - A23D 9/007: characterised by ingredients other than fatty acid triglycerides - A23L 33/115: Fatty acids or derivatives thereof; Fats or oils - A23L 33/12: Fatty acids or derivatives thereof - A23P 10/30: Encapsulation of particles, e.g. foodstuff additives - A61K 8/11: Encapsulated compositions - A61K 8/361: {Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof} - A61K 8/40: containing nitrogen (quinones containing nitrogen A61K8/355) - A61K 8/922: {of vegetable origin} - A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)} - A61K 31/201: having one or two double bonds, e.g. oleic, linoleic acids - A61K 31/202: having three or more double bonds, e.g. linolenic (eicosanoids, e.g. leukotrienes A61K31/557) - A61K 35/60: Fish, e.g. seahorses; Fish eggs - A61K 36/28: Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea - A61K 36/55: Linaceae (Flax family), e.g. Linum - A61Q 7/00: Preparations for affecting hair growth - A61Q 19/00: Preparations for care of the skin - A61Q 19/007: {Preparations for dry skin} - A61Q 19/008: {Preparations for oily skin} - A61Q 19/08: Anti-ageing preparations - C11C 3/00: Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom (sulfonated fats or oils C07C309/62; factice C08H; drying oils C09F) - A23V 2002/00: Food compositions, function of food ingredients or processes for food or foodstuffs - A61K 2800/92: Oral administration - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A23D: EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS (preservation thereof A23B20/00; production, refinement or preservation of animal or vegetable fats or oils C11B, C11C) - A23L: FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF (preservation thereof A23B) - A23P: SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS - A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS - C11C: FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM - A23V: INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION ## Abstract Compositions, dietary supplement compositions, and topical compositions including activated fatty acids and methods for using activated fatty acids to treat a variety of diseases. ## Claims ### Claim at position 1 -101. (canceled) ### Claim 102 A composition comprising an effective amount of at least one activated fatty acid and an alimentary oil. ### Claim 103 (depends on 102) The composition of claim 102, wherein an alimentary oil is either a plant oil, an animal fat or a combination thereof. ### Claim 104 (depends on 102) The composition of claim 102 wherein the activated fatty acid is nitrated α-linoleic acid, nitrated γ-linoleic acid, nitrated oleic acid, nitrated eicosapentaenoic acid, nitrated docosahexaenoic acid or a derivative or combination thereof. ### Claim 105 (depends on 102) The composition of claim 102, wherein the alimentary oil is olive oil. ### Claim 106 A method of nitrating an alimentary oil comprising contacting the alimentary oil with an oxide of nitrogen. ### Claim 107 (depends on 106) The method of claim 106 wherein, the alimentary oil is olive oil, flaxseed oil, fish oil or a combination thereof. ### Claim 108 (depends on 106) The method of claim 106 wherein the oxide of nitrogen is NO, NO3−, NO2, HNO2, NO2+ or combination thereof. ### Claim 109 (depends on 106) The method of claim 106, wherein nitration occurs at an acidic pH. ### Claim 110 (depends on 109) The method of claim 109, wherein the pH is less than 4.0. ### Claim 111 A composition comprising: an alimentary oil, one or more nitrated fatty acid and one or more unsaturated fatty acid. ### Claim 112 (depends on 111) The composition of claim 111 wherein the alimentary oil is olive oil, the nitrated fatty acids are nitro-linoleic acid, nitro-oleic acid or a combination thereof and the unsaturated fatty acids are linoleic acid, oleic acid or a combination thereof. ### Claim 113 (canceled) ### Claim 114 (canceled) ### Claim 115 (depends on 111) The composition of claim 111, wherein the alimentary oil is flaxseed oil, the nitrated fatty acids are nitro-linoleic acid, nitro-oleic acid or a combination thereof and the unsaturated fatty acids are linoleic acid, oleic acid or a combination thereof. ### Claim 116 (canceled) ### Claim 117 (canceled) ### Claim 118 (depends on 111) The composition of claim 111, wherein the alimentary oil is docosahexaenoic acid, the nitrated fatty acid is nitro-docosahexaenoic acid and the unsaturated fatty acid is docosahexaenoic acid. ### Claim 119 (depends on 111) The composition of claim 111, wherein the alimentary oil is fish oil, the nitrated fatty acid is nitro-docosahexaenoic acid, nitrated eicosapentaenoic acid, nitro-linoleic acid, nitro-oleic acid or a combination thereof and the unsaturated fatty acid is docosahexaenoic acid, eicosapentaenoic acid, linoleic acid, oleic acid or a combination thereof. ### Claim at position 20 -125. (canceled) ### Claim 126 (depends on 111) The composition of claim 111, wherein the alimentary oil is safflower oil, the nitrated fatty acid is conjugated linoleic acid, nitro-linoleic acid, nitro-oleic acid or a combination thereof and the unsaturated fatty acid is conjugated linoleic acid, linoleic acid, oleic acid or a combination thereof. ### Claim at position 22 -151. (canceled)