Formulations and Methods for Increasing or Reducing Mucus
AssigneeForSight Vision5, Inc.
InventorsCary J. Reich, K. Angela Macfarlane, Yair Alster, Logan Stark
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Abstract
The present disclosure is directed to a pharmaceutical delivery device useful for the treatment of ocular diseases and disorders through sustained release of therapeutic doses of a pharmaceutical agent, while increasing or reducing formation and/or accumulation of mucus.
Claims45
A ring shaped ocular insert for increasing mucus in the eye of a subject, comprising a polymer matrix and an excipient chosen from a colorant or dye, oil, lipid, fatty acid, fatty alcohol, and water soluble polymer.
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A ring shaped ocular insert for treating dry eye and/or related syndromes, comprising a polymer matrix comprising an excipient chosen from a colorant or dye, oil, lipid, fatty acid, fatty alcohol, and water soluble polymer.
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A method of treating dry eye and/or related syndromes of a subject in need thereof comprising placing an ocular insert into the eye of a subject in thereof, wherein the ocular insert comprises a polymer matrix and an excipient chosen from a colorant or dye, oil, lipid, fatty acid, fatty alcohol, and water soluble polymer.
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A method of increasing mucus formation and/or accumulation in the eye of a subject in need thereof, comprising placement of a ring shaped pharmaceutical agent delivery device, wherein the device is prepared with a polymerizable or non-polymerizable fluid and comprises an excipient and a pharmaceutical agent, wherein the excipient increases production and/or accumulation of mucus after the device is placed in the eye of the subject.
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A ring shaped ocular insert for reducing mucus in the eye of a subject comprising a polymer matrix and an excipient chosen from a colorant or dye, oil, lipid, fatty acid, fatty alcohol, and water soluble polymer.
Dependencies are inferred from the claim text.