Pharmaceutical gels and methods for delivering therapeutic agents to a site beneath the skin
AssigneeWarsaw Orthopedic, Inc.
InventorsJohn M. Zanella, William F. McKay
Life of this patent
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Abstract
Pharmaceutical gels and methods for delivering a therapeutic agent to a target tissue site beneath the skin of a patient are provided, the gel being capable of adhering to the target tissue site and comprising one or more biodegradable depots containing an effective amount of the therapeutic agent. In various embodiments, the gel is sprayable and hardens after contacting the target tissue site.
Claims20
A gel for delivering a therapeutic agent to a target tissue site beneath the skin of a patient, the gel being capable of adhering to the target tissue site and comprising one or more biodegradable depots containing an effective amount of the therapeutic agent, wherein the target tissue site comprises at least one muscle, ligament, tendon, cartilage, spinal disc, spinal foraminal space near the spinal nerve root, facet or synovial joint, or spinal canal.
A method for delivering a therapeutic agent into a synovial joint of a patient, the method comprising inserting a cannula at or near a target tissue site in the synovial joint and spraying a gel capable of adhering to the target tissue site in the synovial joint, the gel comprising one or more biodegradable depots containing an effective amount of the therapeutic agent.
A method for delivering a therapeutic agent into a target tissue site beneath the skin, the method comprising inserting a cannula at or near the target tissue site;
- and injecting a gel capable of adhering to the target tissue site, the gel comprising one or more biodegradable depots containing an effective amount of the therapeutic agent, wherein the target tissue site comprises a spinal disc, spinal foraminal space near the spinal nerve root, facet joint, spinal canal, or bone.
Dependencies are inferred from the claim text.