Extracts from plants of the moringaceae family and methods of making
AssigneeRutgers, The State University of New Jersey
InventorsIlya Raskin, Carrie Waterman
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Abstract
The present application is directed to materials and methods for producing extracts from a plant of the Moringaceae family having high concentrations of moringa isothiocyanates. The present disclosure is based in part on the discovery that the enzyme necessary to convert moringa glucosinolates (MGLs) into moringa isothiocyanates (MICs) (i.e., myrosinase) can be activated by simply injuring fresh leaves or sprouts of a plant of the Moringaceae family, without first subjecting the plant material to harsh conditions, such as harsh temperatures and drying conditions.
Claims31
A method of activating myrosinase present in a plant of the Moringaceae family comprising injuring fresh leaves or sprouts of the plant at a temperature of less than 100° C. for a time sufficient to activate myrosinase present in the plant.
A method of producing a plant composition comprising injuring fresh leaves or sprouts of a plant of the Moringaceae family at a temperature of less than 100° C. to produce the plant composition, wherein the plant composition comprises at least 0.1 wt % moringa isothiocyanates.
A method of producing an extract from a plant of the Moringaceae family comprising:
- contacting fresh injured leaves or sprouts of a plant of the Moringaceae family with an extraction fluid comprising water at a temperature of less than 100° C. to produce an extraction mixture;
- and
- separating solid leaves or sprouts from the extraction mixture to produce the extract.
A method of producing an extract from a plant of the Moringaceae family comprising
- injuring fresh leaves or sprouts of the plant;
- drying the injured fresh leaves or sprouts;
- contacting dried injured leaves or sprouts with an extraction fluid comprising water at a temperature of less than 100° C. to produce an extraction mixture;
- and
- separating solid leaves or sprouts from the extraction mixture to produce the extract.
The extract of 18, wherein the MICs are selected from the group consisting of 4-[(α-L-rhamnosyloxy)benzyl] isothiocyanate (MIC-1) and 4-[(4′-O-acetyl-α-L-rhamnosyloxy)benzyl] isothiocyanate (MIC-4).
Dependencies are inferred from the claim text.