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US 2016/0243157 A1Published application
Polymeric treatment compositions
AssigneeMicroVention, Inc.
InventorsGregory M. Cruise, Michael J. Constant, Joshua Garretson
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Abstract
Compositions are described comprising a polymer; a non-physiological pH solution; and a visualization agent; wherein the polymer is soluble in the non-physiological pH solution and insoluble at a physiological pH. Methods of forming the solutions and polymers are disclosed as well as methods of therapeutic use.
Claims20
A method of delivering a composition comprising:
- injecting through a delivery device into a location with physiological pH environment a liquid embolic composition comprising a polymer, a non-physiological pH solution and a visualization agent,
- wherein the polymer precipitates when it reaches the physiological pH.
A method of treating a vascular disorder comprising
- providing a liquid embolic composition comprising a biocompatible polymer, a non-physiological pH solution and a visualization agent, wherein the biocompatible polymer is soluble in the non-physiological pH solution and insoluble in a physiological pH;
- inserting a delivery device into a vessel;
- guiding the delivery device to an area in need of treatment wherein the area has a physiological pH;
- injecting the liquid embolic polymer composition through the delivery device into the vessel at the area in need of treatment thereby immediately precipitating the polymer and forming a solid polymeric mass;
- and
- treating the vascular condition.
3 more elements
Dependencies are inferred from the claim text.