Methods and Compositions for Treating Dry Eye Disease and Other Eye Disorders
AssigneesThe Board of Trustees of the University of Illinois, Ocugen, Inc.
InventorsSandeep Jain, Uday Bhaskar Kompella, Shankar Musunuri
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Abstract
The present invention discloses pharmaceutical preparations for treatment of eye disorders containing an alpha 2 adrenergic agonist, to processes for producing the pharmaceutical preparations and methods for treatment of various eye disorders including dry eye and Meibomian gland dysfunction and a medicinal applicator for topical application of an alpha 2 adrenergic agonist to a subject, a package assembly for the medicinal applicator and methods of using the medicinal applicator to treat eye disorders.
Claims30
A method of treating a patient suffering from a dry eye syndrome comprising administering to an eye of the patient in need of such a treatment an ophthalmological pharmaceutical formulation comprising a therapeutically effective amount of an alpha 2 adrenergic agonist or a pharmaceutically acceptable salt thereof.
The method of claim 7, wherein the ADDE is oGVHD.
A method of treating Meibomian gland dysfunction (MGD) in a subject in need thereof comprising applying a therapeutically effective amount of an alpha 2 adrenergic agonist to each eye of the subject.
An ophthalmic topical composition comprising an alpha 2 adrenergic agonist and mineral oil or petrolatum jelly.
A method of treating a patient suffering from a dry eye syndrome, said method comprising administering to an eye of the patient in need of such a treatment an ophthalmological pharmaceutical formulation comprising a therapeutically effective amount of brimonidine or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.