Transdermal patch and method for delivery of vitamin b12
AssigneeVita Sciences LLC
InventorJon ZELTMAN
Life of this patent
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Abstract
The present invention is directed to compositions and devices for transdermally administering vitamin B12 to a subject. In one aspect, a vitamin B12 containing composition suitable for transdermal administration is provided in the form of a shelf stable transdermal delivery patch. Such patches contain vitamin B12 combined with selected penetration enhancers and vitamin B12 stabilizers.
Claims18
A shelf stable transdermal delivery patch for administering vitamin B12 to a subject, comprising:
- (a) a backing layer;
- (b) a skin contact adhesive layer adjacent to the backing layer, said skin contact adhesive layer including:
- (i) a polymeric adhesive;
- (ii) vitamin B12;
- (iii) a penetration enhancer effective to enhance transdermal uptake of vitamin B12 by said subject;
- and
- (iv) a vitamin B12 stabilizer to stabilize the vitamin B12 contained within the adhesive layer;
- and
- (c) a removable impermeable layer overlaying the skin contact adhesive layer, said removable impermeable layer preventing vitamin B12 release from the skin contact adhesive layer prior to use.
A method of transdermally administering vitamin B12 to a subject, comprising contacting a subject's skin with a composition including:
- (a) a polymeric adhesive;
- (b) vitamin B12;
- (c) a penetration enhancer effective to enhance transdermal uptake of the vitamin B12 by said subject;
- and
- (d) a vitamin B12 stabilizer to stabilize the vitamin B12 contained within the composition;
- wherein said vitamin B12 is transdermally administered to said subject.
A shelf stable transdermal delivery patch provided by the method set forth in claim 19.
Dependencies are inferred from the claim text.