Method of making particles for use in a pharmaceutical composition
AssigneeVectura Limited
InventorsJOHN NICHOLAS STANIFORTH, MATTHEW MICHAEL GREEN, DAVID ALEXANDER VODDEN MORTON
Life of this patent
Estimating the term…
Abstract
The invention relates to a method for making composite active particles for use in a pharmaceutical composition for pulmonary administration, the method comprising a milling step in which particles of active material are milled in the presence of particles of an additive material which is suitable for the promotion of the dispersal of the composite active particles upon actuation of an inhaler. The invention also relates to compositions for inhalation prepared by the method.
Claims13
Composite active particles for use in a pharmaceutical composition for pulmonary administration, each composite active particle comprising a particle of active material and particles of an additive material on the surface of the particle of active material, the composite active particles having a mass median aerodynamic diameter of not more than 10 μm, wherein the additive material comprises a metal stearate.
Dependencies are inferred from the claim text.