Back to results
US 2016/0243029 A1Published application
Method of treating middle ear infections
AssigneeAlcon Pharmaceuticals Ltd.
InventorsG. Michael Wall, Peter J. Conroy
Life of this patent
Estimating the term…
Abstract
Aqueous suspension formulations containing dexamethasone and ciprofloxacin are disclosed for the treatment of middle ear infections in human patients having an open tympanic membrane.
Claims23
A method of treating a human patient comprising the steps of:
- (a) diagnosing the patient as having otitis media and an open tympanic membrane and/or having acute otitis externa in at least one ear;
- and
- (b) topically applying into the ear canal of the patients ear an aqueous suspension composition containing a combination of ciprofloxacin and dexamethasone, wherein the composition comprises a) 0.01-0.5% (wt.) dexamethasone;
- b) 0.1-0.4% (wt.) ciprofloxacin;
- c) 0.1-0.9% (wt.) tonicity agent;
- d) 0.01-0.2% (wt.) of a nonionic surfactant;
- and e) a buffer;
- wherein three or four drops of the aqueous suspension composition are administered to the patients ear twice a day, and wherein each drop is 30-35 μL.
5 more elements
A kit for treating otic infections, the kit comprising an aqueous suspension composition comprising a) 0.01-0.5% (wt.) dexamethasone;
- b) 0.1-0.4% (wt.) ciprofloxacin;
- c) 0.1-0.9% (wt.) tonicity agent;
- d) 0.01-0.2% (wt.) of a nonionic surfactant;
- and e) a buffer, said composition in a sealed container together with instructions for use thereof, and wherein said instructions indicate that four drops of the aqueous suspension composition are administered to a patients ear twice a day and/or wherein said instructions indicate that three drops of the aqueous suspension composition are administered to a patients ear twice a day.
1 more element
Dependencies are inferred from the claim text.