Voxel-Resolution Myocardial Blood Flow Analysis

A non-transitory computer readable medium storing instructions that cause a processing device, in response to executing the instructions, to perform operations comprising:

• the processing device applying a pharmacological kinetic model to a data set stored in a storage device, the data set derived from an imaging technique based on monitoring fluid based tracers in a left ventricle, a right ventricle, and myocardium, wherein the pharmacological kinetic model includes:
• incorporating a model of changing concentrations of bound fluid based tracers, unbound fluid based tracers, and blood plasma fluid based tracers into a standard factor analysis of dynamic structures model without assumption that a right ventricle tissue curve and a left ventricle tissue curve obey a particular mathematical relationship, and;
• the processing device outputting a processed data set based on the application of the pharmacological kinetic model to the data set for providing a representation of blood flow in the myocardium.

An apparatus comprising:

• a processing device configured to apply a pharmacological kinetic model to a data set stored in a storage device, the data set derived from an imaging technique based on monitoring fluid based tracers in a left ventricle, a right ventricle, and myocardium, wherein the pharmacological kinetic model includes:
• incorporating a model of changing concentrations of bound fluid based tracers, unbound fluid based tracers, and blood plasma fluid based tracers into a standard factor analysis of dynamic structures model without assumption that a right ventricle tissue curve and a left ventricle tissue curve obey a particular mathematical relationship, and;
• the processing device configured to output a processed data set based on the application of the pharmacological kinetic model to the data set for providing a representation of blood flow in the myocardium.