Methods for diagnosing chronic valvular disease
AssigneeNestec S.A.
InventorQinghong Li
Life of this patent
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Abstract
The invention provides methods for diagnosing chronic valvular disease in an animal. The methods comprise obtaining a sample from the animal; analyzing the sample for an amount of a microRNA (miRNA) associated with chronic valvular disease; comparing the amount of the miRNA identified in the sample to a corresponding amount of the miRNA present in a sample from one or more comparable control animals that do not suffer from chronic valvular disease; and diagnosing the animal with chronic valvular disease if the amount of the miRNA found in the animal's sample is differentially expressed in the control animal's sample.
Claims16
A method for diagnosing chronic valvular disease in an animal comprising:
- a. obtaining a biological sample from the animal;
- b. analyzing the biological sample for an amount of a microRNA (miRNA) associated with chronic valvular disease;
- c. comparing the amount of the miRNA identified in the sample to a corresponding amount of the miRNA present in a sample from one or more comparable control animals that do not suffer from chronic valvular disease;
- and
- d. diagnosing the animal with chronic valvular disease if the amount of the miRNA found in the animal's sample is greater than the amount of the miRNA present in the control animal's sample.
A method for diagnosing chronic valvular disease in an animal comprising:
- a. obtaining a biological sample from the animal;
- b. analyzing the biological sample for an amount of a microRNA (miRNA) associated with chronic valvular disease;
- c. comparing the amount of the miRNA identified in the sample to a corresponding amount of the miRNA present in a sample from one or more comparable control animals that do not suffer from chronic valvular disease;
- and
- d. diagnosing the animal with chronic valvular disease if the amount of the miRNA found in the animal's sample is less than the amount of the miRNA present in the control animal's sample.
Dependencies are inferred from the claim text.