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US 2016/0237494 A1Published application
Methods for Selecting Medications
AssigneeMayo Foundation for Medical Education and Research
InventorsDavid A. Mrazek, Dennis J. O'Kane, John L. Black
Life of this patent
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Abstract
The invention provides computer assisted methods for selecting an antidepressant medication for a patient. The methods utilize a combination genotype comprising at least three genes to guide medication selection.
Claims13
1-47. (canceled)
A computer-implemented method for selecting an antidepressant medication for a patient in need thereof, the method comprising
- identifying the patient's clinical phenotype as depression based on data received by the computer system,
- receiving a set of medications used to treat depression,
- associating each of the medications with a combination genotype and a category of use to create at least one medication profile for each medication, the combination genotype comprising the genotypes of a panel of at least three genes, a cytochrome P450 CYP2D6 gene, a cytochrome P450 CYP2C19 gene, and a serotonin transporter gene 5HTTR,
- storing the medication profiles and genotypes such that a medication profile associated with a specific genotype can be identified,
- receiving the patient's combination genotype for the panel of at least three genes,
- identifying from the stored medication profiles at least one identified medication profile associated with the patient's combination genotype, and
- outputting a patient-specific report comprising the at least one identified medication profile associated with the patient's genotype.
4 more elements
Dependencies are inferred from the claim text.