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US 2016/0237435 A1Published application
Multiaptamer Target Detection
AssigneeSomaLogic, Inc.
InventorsUrs A. Ochsner, Louis S. Green, Larry Gold, Nebojsa Janjic
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Abstract
Described herein are compositions comprising a first aptamer, second aptamer and a target that are capable of forming a ternary complex, and wherein the first aptamer and the second aptamer comprise C-5 pyrimidine modification schemes that are different, and methods of making and using such compositions.
Claims24
A composition comprising a first aptamer, second aptamer, and a target,
- wherein the first aptamer comprises a first C-5 pyrimidine modification scheme, the second aptamer comprises a second C-5 pyrimidine modification scheme, and wherein the first C-5 pyrimidine modification scheme and the second C-5 pyrimidine modification scheme are different;
- and
- wherein the first aptamer, second aptamer and the target are capable of forming a ternary complex.
24-49. (canceled)
Dependencies are inferred from the claim text.