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US 2016/0237137 A1Published application
Nanoparticle Based Artificial Antigen Presenting Cell Mediated Activation of NKT Cells
AssigneeUniversity of Maryland, Baltimore
InventorsTonya Webb, Carolyn Morris, James East
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Abstract
The present invention relates to, in part, artificial antigen presenting cells that are useful in treating disease (including cancers) and have uses, for example, directly in vivo and/or in the expansion of a patients cells for re-introduction ex vivo.
Claims21
A microparticle or nanoparticle, comprising on its surface:
- (a) a population of antigen presenting complexes that activate T cell receptors (TCRs) of NKT cells and
- (b) a population of NKT cell costimulatory ligands.
-43. (canceled)
Dependencies are inferred from the claim text.