Back to results
US 2016/0237128 A1Published application
Optically transparent silk hydrogels
AssigneeTufts University
InventorsFiorenzo G. Omenetto, David L. Kaplan, Benedetto Marelli, Alexander Nicholas Mitropoulos
Life of this patent
Estimating the term…
Abstract
The present application relates to silk fibroin-based hydrogels, methods for making and using the same.
Claims62
A silk fibroin-based hydrogel, having at least 60% transmittance in a visible spectrum.
A silk fibroin-based hydrogel, comprising:
- silk fibroin polypeptides that have an average molecular weight in a range of about 3.5 kDa and about;
- and
- nanosized crystalline particles are in a range of about 10 nm and about 150 nm, wherein the hydrogel is characterized by an optical transmittance in the visible spectrum between at least 40% and at least 99%.
A method of manufacturing a silk fibroin-based hydrogel, comprising steps of:
- providing a silk fibroin solution, wherein the solution comprises silk fibroin polypeptides that have an average molecular weight of less than about 350 kDa;
- and
- mixing the silk fibroin solution with a polar organic solvent, so that silk fibroin polypeptides form nanosized crystalline particles with a diameter of less than about 200,
- wherein the hydrogel is characterized by optical transmittance in the visible spectrum of at least 40%.
1 more element
Dependencies are inferred from the claim text.