C-Met Protein Agonist
AssigneeThe University of Tokyo
InventorsHiroaki SUGA, Kenichiro ITO
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Abstract
Object of the present invention is to provide a peptide functioning as a c-Met agonist. The present invention provides a peptide complex comprising two or more peptides that bind to a c-Met protein and a linker that links the two or more peptides to one another. Such a peptide complex promotes autophosphorylation of the c-Met protein and induces cell growth.
Claims13
A peptide complex comprising two or more peptides that bind to c-Met proteins and a linker that links the two or more peptides to one another.
A method for producing a peptide that binds to a target substance and has high stability, comprising following steps:
- N-methylating or N-alkylating at least one amino acid residue of a peptide that binds to the target substance,
- cyclizing the peptide;
- and
- evaluating the stability of the peptide.
Dependencies are inferred from the claim text.