Substituted phenylalanine derivatives

A compound of the formula

• in which
• R1 represents a group of the formula
• where # is the point of attachment to the nitrogen atom,
• R5 represents 5-membered heteroaryl,
• where heteroaryl may be substituted by a substituent selected from the group consisting of oxo, chlorine, cyano, hydroxy and C1-C3-alkyl,
• in which alkyl may be substituted by 1 to 3 substituents independently of one another selected from the group consisting of hydroxy, amino, hydroxycarbonyl and methoxy, or
• in which alkyl may be substituted by 1 to 7 fluorine substituents, or
• in which alkyl is substituted by a substituent selected from the group consisting of hydroxy, amino, hydroxycarbonyl and methoxy, and in which alkyl is additionally substituted by 1 to 6 fluorine substituents,
• R6 represents hydrogen, fluorine or chlorine,
• R7 and Rg together with the carbon atoms to which they are attached form a 5-membered heterocycle,
• where the heterocycle may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of oxo, chlorine, cyano, hydroxyl, C1-C3-alkyl, pyrazolyl and pyridyl,
• in which alkyl may be substituted by 1 to 3 substituents independently of one another selected from the group consisting of hydroxy, amino, hydroxycarbonyl and methoxy, or
• in which alkyl may be substituted by 1 to 7 fluorine substituents, or
• in which alkyl is substituted by a substituent selected from the group consisting of hydroxy, amino, hydroxycarbonyl and methoxy, and in which alkyl is additionally substituted by 1 to 6 fluorine substituents,
• R9 represents hydrogen, fluorine or chlorine,
• R2 represents hydrogen, fluorine, chlorine, methyl or methoxy,
• R3 represents hydrogen, fluorine, chlorine, C1-C4-alkyl, methoxy or trifluoromethyl,
• R4 represents amino, cyano, C1-C3-alkoxy, C1-C3-alkylamino, C1-C3-alkoxycarbonyl, C1-C3-alkylcarbonylamino, C1-C3-alkylsulphonyl, —S(O)2NR10R11 or 5- to 7-membered heterocyclyl which is attached via a nitrogen atom,
• where alkoxy may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of fluorine, hydroxy, amino, hydroxycarbonyl, C1-C3-alkoxy, C1-C3-alkylamino, difluoromethyl, trifluoromethyl, —(OCH2CH2)n—OCH3, —(OCH2CH2)m—OH, morpholinyl, piperidinyl and pyrrolidinyl,
• in which n is a number from 1 to 6,
• in which m is a number from 1 to 6, and
• where alkylcarbonylamino may be substituted by a —NH(CO)CH2NH(CO)CH2NH2 substituent, and
• where heterocyclyl may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of oxo, chlorine, cyano, hydroxy and C1-C4-alkyl, and
• where
• R10 represents hydrogen, C1-C3-alkyl, C3-C6-cycloalkyl, benzyl or 4- to 8-membered heterocyclyl which is attached via a carbon atom,
• in which alkyl may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of hydroxy, amino, hydroxycarbonyl and methoxy, and
• in which cycloalkyl may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of oxo, fluorine, hydroxy, amino, C1-C4-alkyl and C1-C3-alkylamino, and
• in which heterocyclyl may be substituted by 1 to 2 substituents independently of one another selected from the group consisting of oxo, chlorine, cyano, hydroxy and C1-C4-alkyl,
• R11 represents hydrogen or C1-C3-alkyl, or
• R10 and R11 together with the nitrogen atom to which they are attached form a 4- to 7-membered heterocycle,
• in which the heterocycle may be substituted by 1 to 2 substituents selected independently from the group consisting of oxo, fluorine, hydroxyl, amino, hydroxycarbonyl, C1-C4-alkyl, C1-C3-alkylamino, difluoromethyl, trifluoromethyl, 2,2,2-trifluoroeth-1-yl, C1-C4-alkoxycarbonyl, aminocarbonyl and C1-C3-alkylaminocarbonyl,
• or one of the salts thereof, solvates thereof or solvates of the salts thereof.