Bone regeneration material and manufacture method thereof
AssigneeWishbone
InventorsEric Rompen, France Lambert, Geoffrey Lecloux, Philippe Moniotte
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Abstract
The invention relates to a method that includes: placing a bone material, containing hydroxyapatite and organic substances, in contact with an extraction liquid that gives rise to a first liquid phase, containing said organic substances and possibly impurities extracted from said bone material, and a second solid hydroxyapatite phase, containing said hydroxyapatite; and separating said liquid phase and said solid hydroxyapatite phase. Said extraction liquid is an aqueous extraction solution brought to a temperature between 150° C. and 300° C. and a pressure between 150 kPa and 350 kPa.
Claims16
A method to manufacture a bone regeneration material, comprising:
- contacting a bone material containing hydroxyapatite and organic substances with an extraction liquid giving rise to a first liquid phase containing said organic substances and optionally impurities extracted from said bone material, and to a second solid hydroxyapatite phase containing said hydroxyapatite;
- and
- separating said liquid phase from said solid hydroxyapatite phase,
- wherein said extraction liquid is an aqueous extraction solution brought to a temperature between 150° C. and 300° C. at a pressure of between 1500 kPa and 3500 kPa, and in that said separated solid hydroxyapatite phase forms said bone regeneration material.
The method according to claim further comprising an additional step of drying said solid hydroxyapatite phase to obtain a dry solid hydroxyapatite phase.
A bone regeneration material comprising a solid hydroxyapatite phase obtained from bone material of natural origin and having identical crystalline structure and morphology to those of said bone material.
Dependencies are inferred from the claim text.