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US 2016/0235772 A1Published application
Dosage Forms for Oral Administration of Zoledronic Acid or Related Compounds for Treating Disease
AssigneeAntecip Bioventures II LLC
InventorHerriot Tabuteau
Life of this patent
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Abstract
Oral dosage forms of bisphosphonate compounds, such as zoledronic acid, can be used to treat or alleviate pain or related conditions. The oral bioavailability of zoledronic acid can be enhanced by administering the zoledronic acid in the disodium salt form
Claims28
A method of delivering zoledronic acid to the blood of a human being comprising:
- orally administering zoledronic acid in the disodium salt form to a human being in need of treatment with zoledronic acid;
- wherein the human being is instructed not to eat or drink for at least 1 hour before and at least 1 hour after the zoledronic acid in the disodium salt form is administered, wherein the zoledronic acid in the disodium salt form is administered in a manner that results in an oral bioavailability of zoledronic acid in the human being of 0.5% to about 4%.
A method of treating pain, comprising orally administering zoledronic acid in the disodium salt form to a human being in need thereof;
- wherein the human being is instructed not to eat or drink for at least 1 hour before and at least 1 hour after the zoledronic acid in the disodium salt form is administered, wherein the zoledronic acid in the disodium salt form is administered in a manner that results in an oral bioavailability of zoledronic acid in the human being of 0.5% to about 4%.
Dependencies are inferred from the claim text.