Back to results
US 2016/0235752 A1Published application
Compositions, methods of use, and methods of treatment
AssigneesUniversity of New Orleans, Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
InventorsBRANKO S. JURSIC, DONNA M. NEUMANN
Life of this patent
Estimating the term…
Abstract
Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the antimicrobial agent, methods of treatment of an infection, methods of treatment using compositions or pharmaceutical compositions, and the like.
Claims25
A composition, comprising an antimicrobial agent having the following structure:
- wherein R1 is selected from the group consisting of:
- H, alkyl, aryl, (CH2)nCOOH with n=1-6, OH, and O-alkyl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- wherein R2 is selected from the group consisting of:
- H, alkyl, aryl, (CH2)nCOOH with n=1-6, OH, and O-alkyl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- wherein R3 is selected from the group consisting of:
- H, alkyl, aryl, and COOH, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- wherein R4 is selected from the group consisting of:
- wherein Y is selected from the group consisting of:
- H, OH, NO2, COOH, halogen, alkyl, and O-alkly, where each alkyl group is independently optionally substituted or unsubstituted, wherein R6 is selected from the group consisting of:
- alkyl, O-alkyl, O-aryl, and aryl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- and wherein R7 is selected from the group consisting of:
- alkyl, O-alkyl, O-aryl, and aryl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted.
9 more elements
A pharmaceutical composition comprising a therapeutically effective amount of an antimicrobial agent, or a pharmaceutically acceptable salt of the antimicrobial agent, and a pharmaceutically acceptable carrier, to treat an infection, wherein the antimicrobial agent has the following structure:
- wherein R1 is selected from the group consisting of:
- H, alkyl, aryl, (CH2)nCOOH with n=1-6, OH, and O-alkyl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- wherein R2 is selected from the group consisting of:
- H, alkyl, aryl, (CH2)nCOOH with n=1-6, OH, and O-alkyl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- wherein R3 is selected from the group consisting of:
- H, alkyl, aryl, and COOH, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- wherein R4 is selected from the group consisting of:
- wherein Y is selected from the group consisting of:
- H, OH, NO2, COOH, halogen, alkyl, and O-alkly, where each alkyl group is independently optionally substituted or unsubstituted, wherein R6 is selected from the group consisting of:
- alkyl, O-alkyl, O-aryl, and aryl, where each of alkyl and aryl group is independently optionally substituted or unsubstituted;
- and wherein R7 is selected from the group consisting of:
- alkyl, O-alkyl, O-aryl, and aryl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted.
9 more elements
A method of treating an infection comprising:
- delivering to a subject in need thereof, a pharmaceutical composition, wherein the pharmaceutical composition includes a therapeutically effective amount of an antimicrobial agent, or a pharmaceutically acceptable salt of the antimicrobial agent, and a pharmaceutically acceptable carrier, to treat the infection, wherein the antimicrobial agent has the following structure:
- wherein R1 is selected from the group consisting of:
- H, alkyl, aryl, (CH2)nCOOH with n=1-6, OH, and O-alkyl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- wherein R2 is selected from the group consisting of:
- H, alkyl, aryl, (CH2)nCOOH with n=1-6, OH, and O-alkyl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- wherein R3 is selected from the group consisting of:
- H, alkyl, aryl, and COOH, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- wherein R4 is selected from the group consisting of:
- wherein Y is selected from the group consisting of:
- H, OH, NO2, COOH, halogen, alkyl, and O-alkly, where each alkyl group is independently optionally substituted or unsubstituted, wherein R6 is selected from the group consisting of:
- alkyl, O-alkyl, O-aryl, and aryl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted;
- and wherein R7 is selected from the group consisting of:
- alkyl, O-alkyl, O-aryl, and aryl, where each of alkyl and aryl groups is independently optionally substituted or unsubstituted.
10 more elements
Dependencies are inferred from the claim text.