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US 2016/0235676 A1Published application
Rehydration of micronized tecovirmimat monohydrate
AssigneeSiga Technologies, Inc.
InventorsShanthakumar R. TYAVANAGIMATT, Matthew Reeves, N K Peter SAMUEL, Steven PRIEBE, Ying TAN, Dennis E. HRUBY
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Abstract
Disclosed are methods for hydration of ST-246 particles comprising exposing said particles to moisture by conveying volumes of air containing moisture.
Claims13
A method of hydrating ST-246 particles comprising exposing said particles to moisture by conveying volumes of air containing moisture to said particles.
A method for reducing the particle size of ST-246 particles comprising:
- (a) micronizing ST-246 micronized using an air jet mill in order to reduce particle size to (D90<10 microns) resulting in ST-246 particles exhibiting some extent of dehydration relative to the ST-246 particles prior to micronization;
- and
- (b) rehydrating said micronized ST-246 particles by exposing said partially dehydrated particles to moisture by conveying volumes of air containing moisture to said dehydrated particles.
Dependencies are inferred from the claim text.