Rapamycin for the Treatment of Lymphangioleiomyomatosis
AssigneeLAM Therapeutics, Inc.
InventorsJonathan M. Rothberg, Henri Lichenstein, Thomas Armer, Lawrence S. Melvin, JR.
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Abstract
The present invention relates to methods and compositions for treating lymphangioleiomyomatosis in a human subject in need of such treatment. The methods comprise administering to the subject via inhalation an aerosol composition comprising rapamycin or a prodrug or derivative (including analog) thereof.
Claims49
A pharmaceutical dry powder composition for pulmonary delivery comprising microparticles of a drug in an amount of 0.1 to 2% (w/w) based upon total weight of the composition, the particles of drug having a mean diameter of from 1 to 5 microns, particles of a carrier, and one or more optional excipients, wherein the drug is sirolimus.
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Dependencies are inferred from the claim text.