Synthetic bone grafts constructed from carbon foam materials
AssigneeCibor, Inc.
InventorsPaul Hastings Wooley, Haiying Yu
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Abstract
A porous, self-sustaining body useful as a scaffold for bone grafting is provided. The scaffold comprises a carbonaceous matrix comprising a continuous phase having a surface and defining a plurality of open spaces throughout the matrix. The internal and external surfaces of the matrix are coated with a layer or film selected from the group consisting of osteogenic materials, therapeutic agents, and combinations thereof. The porous body comprises organic materials and is substantially free of metals. Methods of making and using the porous self-sustaining body are also provided, along with kits for facilitating the same.
Claims20
An implant for bone grafting in a subject comprising a porous self-sustaining body comprising:
- a carbonaceous matrix formed of carbon foam and/or graphite foam, said matrix comprising a continuous phase having a surface and defining a plurality of open spaces throughout said matrix, wherein said open spaces comprise pores in said matrix, and
- a coating immobilized on the continuous phase surface of the matrix, said coating being selected from the group consisting of osteoconductive materials, osteoinductive materials, biologics, small molecule drugs, and combinations thereof;
- wherein said porous body is substantially free of metal structures or supports in, on, or through the body.
Dependencies are inferred from the claim text.