Papaya mosaic virus and virus-like particles in cancer therapy
AssigneeFolia Biotech Inc.
InventorsAlain LAMARRE, Denis LECLERC
Life of this patent
Estimating the term…
Abstract
Papaya mosaic virus and virus-like particles (VLPs) comprising ssRNA for use to inhibit cancer growth and metastasis. The PapMV and PapMV VLPs may be used alone or in combination with another cancer therapy, such as a chemotherapeutic, immunotherapeutic, or radiotherapy.
Claims54
A composition comprising papaya mosaic virus (PapMV) or PapMV virus-like particles (VLPs) comprising ssRNA for use in the treatment of cancer in a subject in need thereof.
A composition comprising papaya mosaic virus (PapMV) or PapMV virus-like particles (VLPs) comprising ssRNA for use to improve a cancer immunotherapy in treatment of cancer in a subject in need thereof.
A composition comprising papaya mosaic virus (PapMV) virus-like particles (VLPs) comprising ssRNA for use in the treatment of cancer in a subject in need thereof, wherein the composition is for intratumoral administration and wherein the composition inhibits growth of the cancer.
A composition comprising papaya mosaic virus (PapMV) virus-like particles (VLPs) comprising ssRNA for use to improve a dendritic cell-based immunotherapy in treatment of cancer in a subject in need thereof.
A method of treating cancer in a subject comprising administering to the subject an effective amount of a composition comprising papaya mosaic virus (PapMV) or PapMV virus-like particles (VLPs) comprising ssRNA.
A method of improving a cancer immunotherapy in treating cancer in a subject comprising administering to the subject an effective amount of a composition comprising papaya mosaic virus (PapMV) or PapMV virus-like particles (VLPs) comprising ssRNA.
A method of treating cancer in a subject comprising administering to the subject an effective amount of a composition comprising papaya mosaic virus (PapMV) virus-like particles (VLPs) comprising ssRNA, wherein the composition is administered intratumorally and wherein the composition inhibits growth of the cancer.
A method of improving a dendritic cell-based immunotherapy in treating cancer in a subject comprising administering to the subject an effective amount of a composition comprising papaya mosaic virus (PapMV) virus-like particles (VLPs) comprising ssRNA.
Dependencies are inferred from the claim text.