Method
AssigneeIsis Innovation Limited
InventorRobert MacLaren
Life of this patent
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Abstract
A method of using a vector comprising a transgene to treat a disease or condition of the eye, the method comprising the steps: (a) administering a solution to a mammalian subject by subretinal injection in an amount effective to at least partially detach the retina to form a subretinal bleb, wherein the solution does not comprise the vector; and (b) administering a medicament composition by subretinal injection into the bleb formed by step (a), wherein the medicament comprises the vector and is injected in an amount effective to treat the disease or condition; wherein the transgene is expressible in cells of the mammalian subject.
Claims29
A method of using a vector comprising a transgene to treat a disease or condition of the eye, the method comprising the steps:
- (a) administering a solution to a mammalian subject by subretinal injection in an amount effective to at least partially detach the retina to form a subretinal bleb, wherein the solution does not comprise the vector;
- and
- (b) administering a medicament composition by subretinal injection into the bleb formed by step (a), wherein the medicament comprises the vector and is injected in an amount effective to treat the disease or condition;
- wherein the transgene is expressible in cells of the mammalian subject.
A method of treatment of a disease or condition of the eye, the method comprising administering a vector comprising a transgene by the steps:
- (a) administering a solution to a mammalian subject by subretinal injection in an amount effective to at least partially detach the retina to form a subretinal bleb, wherein the solution does not comprise the vector;
- and
- (b) administering a medicament composition by subretinal injection into the bleb formed by step (a), wherein the medicament comprises the vector and is injected in an amount effective to treat the disease or condition;
- wherein the transgene is expressible in cells of the mammalian subject.
Dependencies are inferred from the claim text.