Method for producing alpha-santalene
AssigneeFirmenich SA
InventorMichel SCHALK
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Abstract
The present invention provides a method of producing α-santalene by contacting at least one polypeptide with farnesyl phyrophosphate (fpp). In particular, the method may be carried out in vitro or in vivo to produce α-santalene, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of a polypeptide useful in the method of the invention. A nucleic acid encoding the polypeptide of the invention and an expression vector containing the nucleic acid represent part of the present invention. A non-human host organism and a cell transformed to be used in the method of producing α santalene are also part of the present invention.
Claims20
A method for producing α-santalene comprising:
- a) contacting FPP with at least one polypeptide having an α-santalene synthase activity and comprising an amino acid sequence at least 50% identical to SEQ ID NO:1;
- b) optionally, isolating the α-santalene produced in step a).
A polypeptide having an α-santalene synthase activity or a (+)-α-santalene synthase activity and comprising an amino acid sequence at least 50% identical to SEQ ID NO:1.
Dependencies are inferred from the claim text.