OXYGEN-TOLERANT CoA-ACETYLATING ALDEHYDE DEHYDROGENASE CONTAINING PATHWAY FOR BIOFUEL PRODUCTION
AssigneeThe Regents of the University of California
InventorsJames C. LIAO, Ethan I. LAN
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Abstract
Provided herein are metabolically-modified microorganisms useful for producing biofuels. More specifically, provided herein are methods of producing high alcohols including isobutanol, 1-butanol, 1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol and 2-phenylethanol from a suitable substrate.
Claims36
A recombinant microorganism the converts a carbon source to a biofuel alcohol comprising a recombinantly expressed oxygen tolerant CoA-acylating aldehyde dehydrogenase (PduP) comprising a sequence that is at least 85% identical to SEQ ID NO:34.
A recombinant vector comprising any two or more genes selected from the group consisting of AccA, AccB, AccC, AccD, nphT7, PhaB, PhaJ, Ter, PduP, and YqhD or any homologs of each of the foregoing.
36-37. (canceled)
Dependencies are inferred from the claim text.