Back to results
US 2016/0109456 A1Published application
Perinucleolar compartment as a cancer marker
AssigneesNorthwestern University, Cold Spring Harbor Laboratory
InventorsSui Huang, Rajesh V. Kamath, David L. Spector, Ann D. Thor, Chen Wang
Life of this patent
Estimating the term…
Abstract
The present invention relates to compositions and methods for cancer diagnostics, prognostics and predictions, including but not limited to, cancer markers. In particular, the present invention provides perinucleolar compartments and their resident molecules as cancer markers.
Claims18
A method for predicting or prognosticating the recurrence or metastases of cancer comprising:
- a) screening a sample from a subject for the presence of perinucleolar compartments;
- and
- b) determining if said subject is susceptible to recurrence or metastases of cancer based on said presence of perinucleolar compartments.
A method for predicting or prognosticating the recurrence or metastases of cancer comprising:
- a) screening a sample from a subject for the expression of PTB;
- and
- b) determining if said subject is susceptible to recurrence or metastases of cancer based on said amount of PTB expression.
A method for screening compounds, comprising:
- a) providing cancer cells and a candidate drug;
- b) exposing said cancer cells to said candidate drug;
- and
- c) detecting the presence of perinucleolar compartments in said cancer cell.
1 more element
-20. (canceled)
Dependencies are inferred from the claim text.