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AssigneeCj Cheiljedang Corporation
InventorsHye Won Kim, Ji Hye Lee, Byeong Cheol Song, Jong Hyun Kim, Han Hyoung Lee, Ae Ji Jeon
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The present invention relates to a novel L-valine-producing strain which is transformed so as to strengthen the expression of L-valine operon by having a nucleotide sequence, for coding a leader peptide in a regulatory region of ilvBN operon, entirely deleted, or partially deleted or substituted. In addition, the present invention relates to a method for producing L-valine using the novel L-valine-producing strain. According to the novel valine-producing strain and the L-valine production method of the present invention using the strain, there is an advantageous effect of producing L-valine at high efficiency and high yield.
An L-valine producing strain transformed to enhance expression of L-valine operon by entirely deleting or partially deleting or substituting a nucleotide sequence encoding a leader peptide in a regulatory region of ilvBN operon, wherein the leader peptide is represented by an amino acid sequence of SEQ ID NO:
A regulatory region variant of L-valine operon having an amino acid sequence represented by SEQ ID No:
Dependencies are inferred from the claim text.