Exosomes from clonal progenitor cells
AssigneeReCyte Therapeutics, Inc.
InventorsDavid Larocca, Mohammad Hassanipour, Paola A. Bignone
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Abstract
The invention provides methods, compositions, uses and kits relating to exosomes isolated from progenitor cells.
Claims24
An exosome isolated from a progenitor cell line.
A method of isolating an exosome from a clonal progenitor cell comprising:
- 1) culturing the clonal progenitor cell in a suitable medium or buffer for a time sufficient to allow the clonal progenitor cell to exocytose exosomes into the culture medium or buffer;
- 2) harvesting the medium or buffer from the cell culture of step 1;
- and 3) isolating the exosomes from the medium or buffer of step 2, thereby isolating an exosome from a clonal progenitor cell.
15-16. (canceled)
19-20. (canceled)
22-35. (canceled)
A method of inducing or enhancing a cell's ability to form vascular tube-like structures comprising contacting a cell capable of making vascular tube-like structures with an exosome isolated from a progenitor cell thereby inducing or enhancing a cell's ability to form vascular tube-like structures.
39-53. (canceled)
Dependencies are inferred from the claim text.