Generation of highly potent antibodies neutralizing the lukgh (lukab) toxin of staphylococcus aureus
AssigneeArsanis Biosciences GmbH
InventorsEszter Nagy, Adriana Badarau, Harald Rouha, Zoltán Magyarics, Sophia Zettl, Michael Benjamin Battles
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Abstract
The subject relates to an isolated Staphylococcus aureus leukocidin antigen comprising a LukGH complex, an antibody specifically binding to the Luk GH complex, and the human CD11b/CD18 complex for use in a method of determining the binding or toxicity of the Staphylococcus aureus Luk GH bi-component cytolysin.
Claims15
An isolated Staphylococcus aureus leukocidin antigen comprising a LukGH complex.
An antibody specifically binding to the LukGH complex.
The human CD11b/CD18 complex for use in a method of determining the binding or toxicity of the Staphylococcus aureus LukGH bi-component cytolysin.
Dependencies are inferred from the claim text.