Peptide stimulator of cell survival and proliferation
AssigneeUniao Quimica Farmaceutica Nacional S/A
InventorMIGUEL GIUDICISSI-FILHO
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Abstract
The invention provides a novel peptide, and derivatives thereof, which is stable in aqueous solution and which stimulates proliferation and survival of endothelial cells and/or fibroblasts. The present peptide can be used at least to promote the S phase of the cell cycle, to stimulate production of extracellular matrix proteins, to reduce apoptosis, to inhibit production of reactive oxygen species and/or to reduce or prevent damage to cell integrity or morphology under stress conditions of serum deprivation.
Claims20
1-2. (canceled)
A peptide consisting of the amino acid sequence DYFKDGKDVN (SEQ ID NO:
- 2).
Dependencies are inferred from the claim text.