Compositions and methods for treating neurodegenerative diseases and cardiomyopathy

A method of treating a neurodegenerative disease or a cardiomyopathy in a patient comprising administering a compound of formula:

• wherein
• Y is NR3 or CR3aR3b;
• L1 is a bond, substituted or unsubstituted alkylene, or substituted or unsubstituted heteroalkylene;
• R1 is hydrogen, oxo, halogen, —CX3, —CN, —SO2Cl, —SO—R10, —SOvNR7R8, —NHNH2, —ONR7R8, —NHC(O)NHNH2, —NHC(O)NR7R8, —NR7R8, —C(O)R9, —C(O)OR9, —C(O)NR7R8, —OR10, —NR7SO2R10, —N(R7)C(O)R9, —NR7C(O)—OR9, —NR7OR9, —OCX3, —OCHX2, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R2 is hydrogen, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R3 is substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R3a and R3b are independently hydrogen, halogen, —CF3, —CCl3, —CBr3, —Cl3, —CN, —OH, —NH2, —COOH, —CONH2, —NO2, —SH, —SO2Cl, —SO3H, —SO4H, —SO2NH2, —NHNH2, —ONH2, —NHC(O)NHNH2, —NHC(O) NH2, —NHSO2H, —NHC(O)H, —NHC(O)—OH, —NHOH, —OCF3, —OCHF2, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• R7, R8, R9, and R10 are independently hydrogen, halogen, —CF3, —CN, —OH, —NH2, —COOH, —CONH2, —NO2, —SH, —SO2Cl, —SO3H, —SO4H, —SO2NH2, —NHNH2, ONH2, —NHC(O)NHNH2, —NHC(O) NH2, —NHSO2H, —NHC(O)H, —NHC(O)—OH, —NHOH, —OCF3, —OCHF2, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;
• where R7 and R8 are bonded to the same nitrogen atom, they may optionally be joined to form a substituted or unsubstituted heterocycloalkyl or substituted or unsubstituted heteroaryl;
• m and v are independently 1 or 2;
• n is independently an integer from 0 to 4;
• X is independently —Cl, —Br, —I, or —F.