Noribogaine salt ansolvates
AssigneeDemerx, Inc.
InventorsRichard D. Gless, JR., William C. Schinzer
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Abstract
Stable noribogaine salt ansolvates are useful for preparing pharmaceutical compositions and for alleviating nociceptive pain in a patient. Such ansolvates can be prepared by slurrying solvated forms, preferably MeOH solvated noribogaine hydrochloride in EtOH/water.
Claims18
A stable pharmaceutically acceptable salt of noribogaine ansolvate.
A crystalline noribogaine hydrochloride solvate polymorph characterized by about 4% weight loss at temperatures under 125° C. in its differential scanning calorimetry thermogram.
A composition comprising the stable noribogaine ansolvate salt of any one of claims 1-8 and 11-14.
A crystalline polymorph of a phosphate salt of noribogaine.
Dependencies are inferred from the claim text.