Methods and apparatuses for remodeling tissue of or adjacent to a body passage

A method for treating a patient, the method comprising:

• (a) advancing a device through a blood vessel to a position within a renal artery, the device comprising:
• (i) an expandable balloon including an outer surface;
• and
• (ii) at least one flexible circuit mounted on the outer surface, including:
• (1) a first insulating layer, (2) at least one heat sensing device positioned at least partially within the first insulating layer, (3) a conductive layer above the first insulating layer, at least a portion of which is electrically coupled to the heat sensing device, (4) a second insulating layer above the conductive layer, and (5) at least one pair of bipolar electrodes associated with the conductive layer;
• (b) expanding the balloon in a renal artery of the patient;
• (c) driving energy through the at least one electrode so as to therapeutically alter at least one nerve proximate the renal artery such that a heart condition of the patient is mitigated.

A method for treating a patient, the method comprising:

• (a) advancing a device to a position within a lumen of the patient's body, the medical device comprising:
• (i) a catheter;
• (ii) an expandable member coupled to the catheter and including an outer surface;
• and
• (iii) at least one flexible circuit mounted on the outer surface of the expandable member, including:
• (1) a first insulating layer, (2) at least one heat sensing device having a first pole and second pole, the heat sensing device positioned at least partially within the first insulating layer, (3) a conductive layer above the first insulating layer, the conductive layer having a first trace connected to the first pole, a second trace connected to the second pole, and a third trace, (4) a second insulating layer above the conductive layer having one or more first openings over the first trace and one or more second openings over the third trace, (5) one or more first electrodes above the second insulating layer conductively coupled to the first trace via the first openings, and (6) one or more second electrodes above the second insulating layer conductively coupled to the third trace via the second openings;
• (b) expanding the expandable member in the lumen of the patient;
• (c) driving energy through the first and second electrodes so as to therapeutically alter at least one nerve proximate the lumen such that a condition of the patient is mitigated.