Method system and device for assessing insulin sensitivity
AssigneeRoche Diabetes Care, Inc.
InventorsOfer Yodfat, Gali Shapira, Iddo Gescheit
Life of this patent
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Abstract
A method and a system for determining insulin sensitivity (IS) is described. In one aspect the method and the system can be implemented by receiving a first parameter corresponding to an insulin dose in a subcutaneous tissue; applying a first kinetic model to obtain a plasma insulin concentration based on the first parameter; receiving a second parameter corresponding to a plasma glucose concentration; determining the insulin sensitivity (IS) based on the plasma insulin concentration and the second parameter.
Claims18
A method for determining an insulin dose to be administered by an insulin delivery device based on a determined insulin sensitivity (IS), comprising:
- providing a subcutaneous glucose sensing apparatus, and the insulin dispensing apparatus;
- and
- receiving a first parameter corresponding to a first insulin dose value administered by the insulin dispensing apparatus in a subcutaneous tissue;
- applying a first kinetic model to obtain a plasma insulin concentration based on the first parameter;
- receiving a second parameter corresponding to a glucose concentration value from the glucose sensing apparatus;
- determining the insulin sensitivity (IS) based on the plasma insulin concentration and the second parameter;
- determining a second insulin dose value based on the determined insulin sensitivity to be administered by the insulin dispensing apparatus;
- and
- reevaluating the insulin sensitivity (IS) after a predetermined period of time since a last food bolus via an insulin sensitivity assessment feature;
- and
- delivering an insulin bolus via a cannula coupled to the insulin delivery apparatus.
A method for determining an insulin dose to be administered by an insulin delivery device based on a determined insulin sensitivity (IS), comprising:
- providing the insulin delivery device comprising a housing containing therein a glucose sensing device and an insulin dispensing apparatus, a cannula extending from the housing;
- receiving a first parameter corresponding to a first insulin dose value administered by the insulin dispensing apparatus in a subcutaneous tissue;
- applying a first kinetic model to obtain a plasma insulin concentration based on the first parameter;
- receiving a second parameter corresponding to a glucose concentration value from the glucose sensing apparatus;
- determining the insulin sensitivity (IS) based on the plasma insulin concentration and the second parameter;
- and
- determining a second insulin dose value based on the determined insulin sensitivity to be administered by the insulin dispensing apparatus.
Dependencies are inferred from the claim text.