Metal-coated scaffolds for tissue engineering
AssigneeRamot at Tel-Aviv University Ltd.
InventorsTal DVIR, Michal SHEVACH, Ben M. MAOZ
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Abstract
Metal nanoparticle-coated scaffolds are provided for use in tissue engineering.
Claims34
A composition of matter comprising viable cells seeded on a scaffold, wherein an outer surface of said scaffold comprises a coating of metal nanoparticles and wherein more than 50% of said metal nanoparticles are positioned on said outer surface of said scaffold.
A scaffold comprising fibers of decellularized extracellular matrix (ECM), wherein an outer surface of said scaffold comprises a coating of metal nanoparticles, with the proviso that said metal nanoparticles are not crosslinked to said scaffold.
A scaffold comprising decellularized omentum, wherein an outer surface of said scaffold comprises a coating of metal nanoparticles.
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A method of generating a scaffold seeded with cells comprising:
- (a) evaporating metal nanoparticles on the outer surface of the scaffold;
- and subsequently
- (b) seeding cells on said scaffold thereby generating the scaffold seeded with cells.
Dependencies are inferred from the claim text.