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US 2016/0106843 A1Published application
Composition, method, and kit for alpha-1 proteinase inhibitor
AssigneeGrifols Therapeutics Inc.
InventorsJianxin Guo, Anthony Klos, Bret Coldren, Deborah Barnette, Mark Manning
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Abstract
The present invention provides compositions comprising API and at least one amino acid, in particular a liquid API formulation comprising amino acids, and methods and kits related thereto. These amino acids when incorporated into the API composition afford stability to the API formulation.
Claims18
1-20. (canceled)
A stable liquid pharmaceutical composition comprising:
- (a) an alpha-1 proteinase inhibitor (API);
- (b) about 0.1M to about 0.3M alanine;
- and
- (c) a pharmaceutically acceptable carrier.
1 more element
A stable liquid pharmaceutical composition consisting essentially of:
- (a) an alpha-1 proteinase inhibitor (API);
- (b) about 0.1M to about 0.3M alanine;
- and
- (c) a pharmaceutically acceptable carrier.
1 more element
A stable liquid pharmaceutical composition consisting essentially of:
- (a) an alpha-1 proteinase inhibitor (API);
- and
- (b) about 0.1M to about 0.3M alanine.
Dependencies are inferred from the claim text.