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US 2016/0106826 A1Published application
Vaccines against pathogenic escherichia coli and methods of using the same
AssigneeQatar University
InventorsHaitham Tawfiq GHUNAIM, Marawan A. ABU MADI, Andrew POTTER, Brenda ALLAN
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Abstract
Provided herein are compositions and methods for vaccinating against infection with pathogenic Escherichia coli (E. coli). In some embodiments, the compositions may include a vaccine including an immunogenic portion of at least two E. coli proteins described herein.
Claims31
A composition comprising at least one of:
- a. an immunogenic portion of at least two isolated proteins selected from a PapG protein, a FimH protein, and an IutA protein, or variants thereof, and
- b. at least one isolated polynucleotide encoding the immunogenic portion of the at least two isolated proteins of (a).
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A polynucleotide encoding an immunogenic portion of PapG and leukotoxin A, FimH and leukotoxin A, or IutA and leukotoxin A.
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Dependencies are inferred from the claim text.