Methods and Compositions for Treating Skin

A method for treating intact irritated or inflamed skin by topically applying a composition that comprises:

• (a) at least one Histamine pathway inhibitor selected from the group consisting of apigenin;
• flavones;
• celery extract;
• parsley extract;
• citrus fruit extracts;
• amentoflavones;
• luteolin, flavinoids;
• phloretins, or 2′,4′,6′,4-Tetrahydroxydihydrochalcones;
• grapeseed extract, Rosmarinus Officinalis extract, or mixtures thereof;
• (b) at least one Chemotaxis pathway inhibitor selected from the group consisting of licorice extract;
• genestein;
• extracts from the genus Scutellaria;
• extracts from the Boswellia genus;
• extract from the Commiphora genus;
• Bursera Microphylla extract;
• Nidularium Proceru extract;
• sequoia extract;
• hypoestoxide;
• Curcuma Longa (turmeric) extract;
• butyloctyl salicylate;
• abyssine;
• plai oil;
• geranium bourbon oil;
• jiagolun EX;
• fucoidan YSK;
• caffeine;
• galactoarabinan;
• lion's mane mushroom extract;
• clerilys extract;
• extracts from Macrycystis Pyrifera;
• reishi mushroom extract;
• Pleurotus Ostreatus extract;
• Hypsizygus Ulmarius extract;
• Cladosiphon Okamuranus Extract;
• Acalypha Wilkesiana extract;
• Acanthopanax Gracilistvlhs extract;
• Allium Sativum extract;
• Ananus Comosus extract;
• Cissampelos Sympodialis extract;
• Coriolus Versicolor extract;
• Echinacea Purpurea extract;
• Grifola Frondosa extract;
• Harpagophvytum Procumbens extract;
• Panax Ginseng extract;
• Polygala Tenuifolia extract;
• Poria Cocos extract;
• Silvbum Marianum extract;
• Smilax Glabra extract;
• Tinospora Cordifolia extract;
• Uncaria Tomentosa extract;
• Withania Somnifera extract;
• slime mold;
• Echinancea extract;
• Viscum Album extract;
• coffee robusta seed extract;
• capsaicin;
• a hexapeptide having the amino acid sequence Val-Gly-Val-Ala-Pro-Gly (VGVAPG);
• ubiquitin;
• nicotinalides;
• cytochalasin B;
• and mixtures thereof;
• (c) at least one Adhesion pathway inhibitor selected from the group consisting of algae extract, neem oil limonoids, Asparagus Racemusus extract, Platycodon Extract, Chaga Mushroom extract, Emblica Officinalis extract, Criste Marine extract, Lavande Papillon extract, Polygonum Cuspidatum, ginger, and mixtures thereof;
• (d) at least one Elastase pathway inhibitor selected from the group consisting of Boswellia Serratia extract, winter begonia extract, oleanolic acid, ursolic acid, phytocohesin, Pygeum Africanum extract, Padina Pavonica extract, Actina Boswellia extract, ligustrum, dipalmitoyl hydroxyproline, Soft Pygeurm extract, chaga mushroom, 7-dehydrocholesterol, white birch extract, polyphenon E, jojoba protein isolate, red raspberry powder, heather extract, hesperitin, hibiscin, mixture of soybean protein and oxido reductases, grapeseed extract, a mixture of butcher's broom extract and heperidin methyl chalcone, hesperidin, caffeine, a protein hydrolysate obtained from extracted organic germinated wheat seeds, hesperitin, glycine soja protein, jojoba oil, Olea Europaea fruit extract, and mixtures thereof;
• (e) at least one Collagenase pathway inhibitor selected from the group consisting of extracts from the Siegesbeckia genus;
• Siegesbeckia Orientalis;
• extracts from the Doliocarpus genus;
• Doliocarpus Verruculosus;
• extracts from the Kaempferia genus;
• Kaempferia galanga root extract;
• extracts from the Camilla genus;
• Camilla Sinensis;
• extracts from the Sauropus genus;
• Sauropus androgynus;
• extracts from the Tetracapidium genus;
• Tetracapidium conophorum;
• glucosamine;
• N-acetyl glucoseamine;
• chondroitan sulfate;
• Pinus Pinaster (pine bark) extract;
• lysine;
• Vitis Vinefera (grape) seed extract;
• retinoids retinyl palmitate;
• retinol;
• retinoic acid;
• extracts from the Pluchea genus;
• Pluchea Indica (Compositae);
• extracts from the Viola genus;
• Viola hondoensis;
• cocoa bean;
• extracts from the Triphala genus;
• Triphala Chebula;
• anthocyanins;
• epigallocatechingallate;
• epicatechingallate;
• luteolin;
• Citri Reticulatae peel extract;
• winter begonia extract;
• extracts from the Tepescohuite genus;
• extracts from the Mimosa genus;
• Mimosa Pudica extract;
• picolinic acid;
• Silymarin extracts;
• Eucommia extracts;
• amentoflavone;
• extracts from the Menyanthes genus;
• Menyanthes Trifoliate extract;
• and mixtures thereof;
• and
• (f) at least one Phosphodiesterase pathway inhibitor selected from the group consisting of nordihydroguaiaretic acid;
• emodin;
• 18-B-glycerrhetinic acid;
• caffeine;
• wild yam powder, Anemarrhena asphodeloides;
• Zhi Mu extract;
• Eucomia extract;
• Uncaria tomentosa;
• and mixtures thereof.