Topically Active Steroids for Use In Interstitial Pulmonary Fibrosis
AssigneeSoligenix, Inc.
InventorGeorge McDonald
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Abstract
The present invention features methods of delivering corticosteroids or metabolites thereof for treating inflammatory conditions otherwise difficult to cure with topical administration.
Claims15
A method of treating an interstitial lung disease comprising oral delivery of an effective amount of a topical active corticosteroid sufficient to expose a metabolite thereof to the pulmonary circulation of a subject.
A method of delivering a corticosteroid or metabolite thereof to a subject's pulmonary artery for treatment of an interstitial lung disease by administering to the subject an effective amount of an oral dosage of the corticosteroid or metabolite.
A method for preventing, ameliorating and/or treating damage resulting from an interstitial lung disease, the method comprising delivering to a subject's pulmonary artery a metabolite of an orally administered corticosteroid in a dose that is at least 5 fold greater than the corticosteroid delivered via inhalation.
Dependencies are inferred from the claim text.