Systems and Methods for Treating an Opioid-Induced Adverse Pharmacodynamic Response
AssigneePurdue Pharma L.P.
InventorsMichele Hummel, Donald J. Kyle, Garth Whiteside
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Abstract
Disclosed in certain embodiments is a method of treating or preventing an opioid induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine.
Claims103
A method of preventing or treating an opioid-induced adverse pharmacodynamic response comprising administering to a patient in need thereof an effective amount of buprenorphine to prevent or treat the adverse pharmacodynamic response induced by the administration of another opioid, wherein the buprenorphine is sub-analgetic.
A pharmaceutical unit dosage form comprising an effective amount of buprenorphine to prevent or treat an adverse pharmacodynamic response induced by another opioid, and a therapeutically effective amount of the other opioid.
A kit comprising (i) a unit dose of an effective amount of buprenorphine to prevent or treat an opioid-induced adverse pharmacodynamic response induced by another opioid and (ii) a unit dose of the other opioid in an effective amount to treat pain, diarrhea, cough or anxiety.
Dependencies are inferred from the claim text.