Solid Dosage Forms of Bendamustine

A pharmaceutical composition in a solid dosage form suitable for oral administration, the composition comprising bendamustine or a pharmaceutically acceptable ester or a salt thereof as an active ingredient, and at least one pharmaceutically acceptable excipient, which is a pharmaceutically acceptable saccharide selected from the group consisting of one or more of a monosaccharide, a disaccharide, an oligosaccharide, a cyclic oligosaccharide, a polysaccharide and a saccharide alcohol, selected from the group consisting of mannitol, maltitol, erythritol, xylitol, lactose, sucrose, glucose, sorbitol, maltose, trehalose, lactitol, dextrose, sucrose 97%+maltodextrin 3%, β-cyclodextrin, D-raffinose pentahydrate and D-melezitose monohydrate and microcrystalline cellulose, wherein the ratio by weight of the active ingredient to the saccharide excipient(s) is in the range of 1:1-5.