Wound healing via autologous stem cell mobilization
AssigneeThe Johns Hopkins University
InventorsZhaoli Sun, George Melville Williams, Qing Lin
Life of this patent
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Abstract
The present invention relates to the field of wound healing. More specifically, the present invention provides methods and compositions useful for improved wound healing via autologous stem cell mobilization. In one embodiment, a method for improving wound healing in a patient comprises administering to the patient a therapeutically effective amount of a stem cell mobilizer and a low dose of an immunosuppressive agent.
Claims26
A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of a stem cell mobilizer and an immunosuppressive agent.
A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of a stem cell mobilizer and a low dose of an immunosuppressive agent.
A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of AMD3100 and a low dose of Tacrolimus.
A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of an agent that mobilizes CD34+ and/or CD133+ stem cells and a low dose of an immunosuppressive agent.
A method for improving wound healing in a patient comprising administering to the patient a low dose of Tacrolimus in an amount sufficient to mobilize stem cells to the peripheral blood of the recipient.
A method for improving wound healing in a patient comprising administering a low dose of Tacrolimus to the patient in an amount sufficient to mobilize CD34+ and/or CD133+ stem cells to the peripheral blood.
A method for improving wound healing in a patient comprising administering Tacrolimus at a dose of about 0.01 mg/kg to about 0.5 mg/kg to the patient, wherein the dosage range is sufficient to mobilize CD34+ and/or CD133+ stem cells to the peripheral blood.
A method for improving wound healing in a patient comprising administering Tacrolimus at a dose of about 0.01 mg/kg to about 0.075 mg/kg to the patient, wherein the dosage range is sufficient to mobilize CD34+ and/or CD133+ stem cells to the peripheral blood.
Dependencies are inferred from the claim text.