Methods for delivering cromolyn

A method of delivering cromolyn to a patient in need thereof, comprising administering to the patient via oral inhalation about 3 mg to about 16 mg of a pharmaceutically acceptable salt or ester of cromolyn, optionally including one or more pharmaceutically acceptable excipients, in the form of a powder comprising particles of the pharmaceutically acceptable salt or ester of cromolyn, the particles having a mass median aerodynamic diameter (MMAD) of about 1 to about 4 microns, using a device that deposits (a) at least 1.5 mg and (b) at least 30% by weight of the administered amount of pharmaceutically acceptable salt or ester of cromolyn to Stage 4 and higher of a Next Generation Pharmaceutical Impactor (NGI) cascade impactor device at a flow rate of 30 L/min for about 4 seconds.

A method of delivering cromolyn to a patient in need thereof, comprising administering to the patient via oral inhalation about 3 mg to about 16 mg of a pharmaceutically acceptable salt or ester of cromolyn, optionally including one or more pharmaceutically acceptable excipients, in the form of a powder comprising particles of the pharmaceutically acceptable salt or ester of cromolyn, the particles having a mass median aerodynamic diameter (MMAD) of about 1 to about 4 microns, using a dry powder inhaler (DPI) device comprising a chamber comprising a piezoelectric vibrator or an ultrasonic vibrator for deaggregating a powder and an air flow passageway in which the deaggregated powder is picked up and carried for oral inhalation by a patient.